纳米银/聚氨酯复合根管充填材料的制备及生物相容性研究
赵泽伟 宗芳 付爽

佳木斯大学口腔医学院，黑龙江佳木斯，154004；

摘要：目的：针对传统根管充填材料生物相容性与抗菌性能难以协同优化的关键问题，开发一种纳米银/聚氨酯复合材料（Ag NPs/PU），并系统评估其理化特性及生物学性能。方法：通过两步法合成聚氨酯基体：制备纯聚氨酯（PU），通过原位负载法掺入纳米银颗粒（Ag NPs）获得复合材料。并表征材料微观结构与元素分布。结果：微观表征：SEM显示Ag NPs/PU表面光滑无缺陷，EDS证实银元素均匀分布；抗菌性能：材料表面检测到特征银元素峰，预示其潜在抗菌功能。结论：本研究成功制备出具有均匀纳米银分布的聚氨酯复合材料，银元素的成功负载为后续抗菌功能开发奠定基础，展现出作为新型根管充填材料的应用潜力。

关键词：聚氨酯复合材料；纳米银；根管微渗漏

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