水晶兰苷抗炎机制研究及其在牙周炎临床治疗中的应用潜力
黄凤 陈海波^{（通讯作者）}

右江民族医学院附属医院口腔科，广西壮族自治区百色市，533000；

摘要：牙周炎是成人失牙主因，现有治疗存骨再生不足、易复发等瓶颈，核心病理为NF-κB通路异常激活，介导炎症与骨代谢失衡恶性循环。水晶兰苷（Monotropein，Mon）为天然环烯醚萜苷类化合物，可抑制NF-κB通路降低促炎因子表达，在多疾病中具抗炎与骨保护活性。鉴于二者高度契合，本文综述水晶兰苷调控NF-κB通路治疗炎症性疾病进展，分析其在牙周炎中的应用潜力。

关键词：水晶兰苷；牙周炎；NF-κB信号通路

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