颅内动脉粥样硬化性狭窄管壁成像相关标志物与卒中关系的研究进展
^{梁美霞1（通讯作者） 于莹2}

1镜湖医院，中国澳门，999078；

2弘爱医院，中国厦门，361000；

摘要：颅内动脉粥样硬化性狭窄是缺血性卒中及短暂性脑缺血发作的核心病因之一，尤其在亚洲人群中占据主导地位。传统影像学评估方法，包括CT血管成像与DSA，虽可精准评估管腔狭窄程度及侧支代偿状态，却无法直接显示血管壁本身的病理解剖学改变。近年来，以高分辨率MR血管壁成像为代表的管壁成像技术，实现了从“管腔中心”向“管壁病理”的范式跃迁，使得识别颅内动脉易损斑块的形态学与组织学特征成为可能。该文综述了颅内动脉粥样硬化性狭窄患者中血管壁影像学生物标志物与卒中发生、进展及复发关系的研究进展，以期为缺血性卒中的早期预防提供参考。

关键词：颅内动脉硬化；血管重构；斑块；颅内狭窄；综述

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