宿主细胞DNA甲基化在宫颈筛查中的临床研究进展
程晨晨 沈芳荣^*

苏州大学附属第一医院，江苏省苏州市，215000；

摘要：宫颈癌严重威胁女性健康，鳞状上皮内病变（Squamous Intraepithelial Lesion，SIL）是其重要癌前阶段。传统宫颈筛查方法存在一定局限性，而宿主细胞DNA甲基化标记在宫颈疾病的早期检测、诊断及管理方面展现出潜在优势。本文综合分析既往相关文献，对宿主细胞DNA甲基化标记在宫颈筛查和SIL的管理中研究进展进行阐述，旨在为临床实践提供参考，推动宫颈疾病防治的发展。

关键词：甲基化；鳞状上皮内病变；宫颈筛查

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